To the long-term users, it brings small increases in muscle and strength, but for the beginners, this substance produces considerably good results with minimal side effects. Gains are very durable. It is pretty much harmless to the liver. Does not aromatises, sometimes there is the occurrence of mild acne, and it does not cause significant increase in blood pressure and cholesterol levels remain normal. Prolonged use slightly affects the formation of testosterone. As the substance is a derivative of DHT, it causes excessive hair growth and for a particular genetic disposition causes excessive hair loss.
Because the oral form is not alkylated and is two times less effective than injection, dose tablets intake must be high. Half-life of methenolone is 10.5 days. It is applied once every 5-7 days at a dose of 400 – 1000 mg per week for men and for women from 50 to 100 mg per week. It should be taken in about 10 to 12 weeks to really achieve its full benefit. The usual dose is 2-6 tablets (100-300 mg) a day in 2-3 doses or 200-400 mg per week in case of injectable version. The reasonable oral dosage is up to 1000 mg per week. Women should not exceed 30 mg a day. Even such a low dosage may cause irreversible virility problems (e.g. deepening of the voice). Primobolone is detectable in the body for up to 6 months.